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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

要知道,从来没有人能够为每一种情况做好万全准备。你可能刚刚发现这一点。你的教育经历为你提供了一个工作基础,但成长往往发生在第一线。或许,你鼓励你的团队不仅按最新期限完成工作,而且表现出色。或许,你与客户共事时发现自己比以往更加镇静自若。或许,你突然发现自己能利用以往建立的人脉,开始在组织里“呼风唤雨”。在学会这些技能之前,你只能学习说“Yes”。面对机会时,感到忐忑不安是很自然的事情,但千万不要让这种情绪扼杀你的成长。
美式快餐发源企业、《财富》美国500强公司麦当劳(McDonald's))上周四宣布,它将用200亿美元进行股票回购和派发股息,由此加入了过去18个月企业界的股票回购浪潮。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

例如,佳士得给威尼斯艺术家弗朗西斯科·丰泰巴索(Francesco Fontebasso)在18世纪中叶创作的油画《井边的丽贝卡和埃利泽》(Rebecca and Eliezer at the Well)的最低估价为12万英镑。根据Artnet的数据,在1990年的拍卖会上,这幅令人愉快的洛可可装饰风格的油画是以28.6万英镑购得的。在12月8日的拍卖会上,它仅得到一个电话出价——11.5万英镑(不含佣金),约合17万美元。而投资者们可不认为在购买沃霍尔(Warhol)或巴斯奎特(Basquiat)的作品25年之后会损失约40%。如果一幅早期绘画大师的作品被搁置在交易商的画廊里,想转卖它就更加困难。
[i'nili]

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

A series of explosions on Aug. 12 that originated in a warehouse illegally storing hazardous chemicals in the port city of Tianjin killed 173 people, injured hundreds and left behind post-apocalyptic scenes of destruction. The blasts raised serious questions about the lax enforcement of safety regulations during China's rapid industrialization.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

一份新发布的研究表明,2014年,全球药品支出将超过万亿美元,治疗丙型肝炎和癌症的创新药品为高价药。截至2018年,预计药品支出费用将再提高三成。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 东莞治理工业“二房东”
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

请做好准备随时当他的救世主。
3.The Jungle Book
9.亲爱的贵客们,我们希望英国能为你们贡献一个美好的夏天,这个夏天包括了顶尖的国际赛事、先进的设施、有趣的娱乐、以及汇集了几个世纪的艺术建筑精华的文化遗产。如果你最终只收获了四张卓著国际中心的摔跤比赛门票,好吧,祝你下次好运。
欧盟的美洲布局

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

15. 有趣的巧合。环球影业是题材最具多样性的制片公司之一,它发行了《生活残骸》,也发行了《冲出康普顿》,还有《泰迪熊2》(Ted 2)。环球影业的女导演也是最多的,12月初,它占据了今年24%的市场份额。
“我非常激动,皮草被禁止参加伦敦时装周是个巨大的进步!” 费斯回应道。
大力优化外商投资环境。
U2乐队主唱波诺、主吉他手"刀刃"和蒂娜·特纳联手合作,共同完成了这首最狂野的007电影主题曲。你会被这首歌的演唱者吸引,并且愿意为她做任何事情。在电影《黄金眼》的主题曲中,蒂娜·特纳在《黄金眼》里面所展现的性感是我们一生都无法企及的。007系列电影主题曲从未如此甜蜜性感,好似歌曲里注入了性激素。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

在周五晚上,金州勇士队以106比94击败了芝加哥公牛队,将战绩提升为14胜0负。库里本场比赛拿下27分,而卫冕冠军也距离NBA历史最佳开局纪录只有一场之遥。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

区块潜力巨大,以至于目前出现了创建更多“侧链”的倡议,尽管该想法存在争议。Chain是一款使创建比特币应用简便化的应用程序接口,该公司首席执行官亚当o卢德温表示:“我们目前并不想干扰主区块。主区块运作良好,我们不想破坏它。”

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

pilot
Data released by the UK National Health Service last year on patient admissions revealed an alarming rise in various nutritional and communicable diseases in the past decade.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
From the themed collection: 土地市场活跃 楼市出现分化
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

temptation
DNA from the bones matched that of descendants of the king's sister, while the skeleton had the twisted spine and battle injuries consistent with contemporary accounts, said researchers from the University of Leicester.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

16. Zapier
n. 小麦,小麦色

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

To SKN Company in Russia for exploding old Russian ammunition and creating diamonds. Now that`s recycling!
v. 引诱,吸引
A vibrant ETF market would depend on the evolution of fee-based distribution networks. Mark Talbot, managing director of Asia-Pacific at Fidelity International, says the distribution infrastructure is holding back retail demand.
在去年的调查中,绝大多数经济学家预期欧洲央行将发起全面量化宽松政策,而今年33个受访者中有几乎快一半的人认为欧洲央行将按兵不动。其他人表示,欧洲央行将扩大量化宽松或下调利率,尽管在那些预期会有更多宽松措施的人中,一部分人强调这家央行不太可能从根本上重塑其现有的政策回应。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

宝能投资集团董事长姚振华是2015年财富榜的黑马,他的财富在一年之内上升了820%,达到172亿美元,使他上升到财富榜第四位。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

说到这一点,你要注意的是,不要影响其他的人。没有人想每隔十分钟就听到你提问一次。如果你实在是不懂的话,可以在课后约上老师再讨论。
近些年来,细菌感染卷土重来,受害者达到了自1960s以来从所未见的最高值,初步确诊者的人数从429跃升至1300多人,从2011年到2017年期间的感染人数翻了两倍不止。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

“…was snervous she almost fainted.”

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 佛山市成立首个情调照明联盟
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

7.Finding Dory

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

We will strive to boost employment and business startups.
8月份,印度所持有的美国政府债券为804亿美元,7月份则为797亿美元。
电视剧版《何以笙箫默》改编自顾漫同名小说,由钟汉良和唐嫣主演,2015年1月首播。它讲述了一对情侣分离7年后重逢,一个执着于等待和相爱的故事。这部小说一直是网络小说中的佼佼者,并于2003年出版。凭借完美情人何以琛一角,演员钟汉良迅速跻身为女粉丝心中的白马王子。
Recent initiatives to support two-way tourism between the two countries include the trial of the 10-year visitor visa; the open aviation market services arrangement which removes all capacity restrictions for airlines on both sides; and a new Beijing to Sydney service by Qantas Airways which was launched in January.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

The Global Obesity Epidemic
4. Am I eating healthy? The types of foods we eat can greatly affect how we feel both physically and emotionally. Eating too much junk food can lead to crankiness and a relatively low energy level, whereas eating healthy foods can lead to better moods and a more positive energy level.
楼市终于出现反弹。S&P/Case-Shiller指数显示,2012年前九个月全国房价上涨7%。与此同时,住宅建筑业正在发力,给建筑工人、承包商和建筑商带来了更多工作机会。5月份以来建筑工作增加了2.9万个左右。券商Miller Tabak & Co.经济学家威尔金森(Andrew Wilkinson)指出,建筑市场的就业环境已经明显解冻。解冻的不只是建筑业。为装修住宅的美国人提供服务的零售企业也将需要招人。[qh]
Around 10 gigabytes of photos have allegedly been released. Jiedaibao, a popular online peer-to-peer lending platform, is involved in the incident, the Beijing Times reported on Dec. 1.
无论你相信与否,今年的搞笑文学奖被授予美国政府审计总署(GAO),以表彰他们发表的有关如何准备一份报告的报告的报告的报告……

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

More than 80 percent of Chinese students returned to the country after completing their studies abroad, and the country has sent 544,500 students in 2016 to study abroad.
3.Porto, Portugal

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

“Someone left for lunch and never came back.”

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

首先,Bitstamp遭遇黑客袭击,以及2011年黑客袭击比特币交易平台Mt. Gox(此次黑客袭击要严重得多,其损失当时约合4亿美元),往往被误解为比特币本身存在安全问题。但事实上,这只能表明上述比特币交易平台存在缺陷,而非比特币技术本身存在问题。而最令人激动的,正是比特币背后的底层技术。正如《财富》杂志2015年1月刊《打造未来》系列报道中所写,大部分极为看好比特币、为其大声疾呼的狂热粉丝(包括马克o安德森这样的大牌企业家,也包括花大把时间更新比特币REDDIT页面的开发者和比特币“矿工”),更感兴趣的是能建立在比特币“区块”(该货币基本骨架)上的应用,而非比特币货币体系。两个实体间可通过“区块”安全交换任何形式的价值。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

发展最迅速的初创公司往往具有全球化的视野。未来一年,美国总统特朗普已经实施的移民限制,以及英国作为退欧的一部分而在考虑的限制措施,可能会对企业招聘形成障碍。
The highest ranked of these is Fudan University School of Management in Shanghai at 40, down eight places on its previous rank in 2014.
Single record of the year: "Over You," Miranda Lambert
Ironically the list comes out the same day that Trump is meeting with Bill Gates, who is the world's richest man for the fourth straight year.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

['elim?nt]
但行业观察人士说,这样的观点忽略了一个中国在创新方面与西方竞争对手直接对峙的领域:让中国版本更具互动性、使用起来也更有趣的那些额外功能。
葡萄牙完全使用可再生能源供电四天
Strachan says that he believes that the IP-BOX uses the same method employed by the FBI to unlock the iPhone 5c used by Syed Farook, without Apple's help. The FBI is now offering to help other law enforcement agencies seeking to unlock an iPhone, iPad or Apple iPod touch. Apple is trying to discover how the FBI unlocked the phone so that it can issue a software update to close the vulnerability.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Most people’s impression of Sweden is that it’s cold, gloomy and beautiful. But that’s not the whole story. As the largest Scandinavian country with a small population, it’s a paradise for people who hate crowds and love their peace and quiet. It’s the perfect setting in which to enjoy the country’s local delicacies, such as fresh seafood, berries, and regional cheeses.
sc=scene(n 风景),roll(n 卷)-卷着风景的画卷

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
From the themed collection: 雄安新区住房将租售并举
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

STEP 9: BE SURE to tell everyone to shut up on a daily basis, it's endearing you know
它还体现在萝塞拉·亚尔迪尼(Rossella Jardini)为莫斯奇诺(Moschino)设计的2009年春夏系列的蝴蝶结和宽松裙子上以及以玛丽·匡特(Mary Quant)为灵感的2013年春季系列中。
May the bright and festive glow of New Year candle warm the days all the year through. Hoping you will have a wonderful time enjoying New Year that is happy in every way.
维多利亚的秘密内衣秀刚刚拉开华丽巨幕,今年的秀也是有史以来最奢华复杂的一次。
While Jaws's story is extremely unrealistic, it was based on a real series of deaths attributed to a single shark in 1916. In what has been dubbed the "most unique set of shark attacks that ever have occurred," the Jersey Shore saw four people die from shark bites over the course of two weeks. The offending shark was reportedly caught with body parts still in its digestive tract, although leading scientists still aren't sure what drove it to attack so many people.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
From the themed collection: 水泥业迎史上最严减排标准
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Vocal duo: Thompson Square
国家统计局中国经济景气监测中心副主任潘建成表示,研发经费与GDP之比不断上升,显示出经济增长正由传统要素(出口和投资)驱动向创新驱动转型。
Her piece, titled “Back to Mother Nature," depicts an elaborate water-cleaning machine. Zhang worked with a team of artists at Google to animate her drawing.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

3. Piggyback Rider
It is up to other institutions — notably, Congress, courts and media — and the citizens at large now to do so.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
From the themed collection: 莫让“以房养老”变了味
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Elsewhere, Dua Lipa, who was up for three gongs, took home the Best New Artist award. While Harry Styles might have a reputation for being one of the most stylish members of One Direction, the Sign of the Times singer had his crown stolen by surprise MTV EMAs newcomer and former band mate, ZAYN.
2017年最佳国家瑞士首度排名第一。瑞士以中立而闻名,“乐于谈生意”排名第三,“公民权益”排名第三。
Other commentators, such as Raoul Leering, head of international trade analysis at ING, the Dutch financial group, fear the outlook is bleak even in the short term.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: 北京某黑中介敲诈勒索租户被公诉
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

吉密欧(Jamil Anderlini)
‘Our hope is that the Worst Passwords of the Year list will cause people to take steps to protect themselves online.’
Interviewers made their share of blunders, too.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 土地估价机构9月底前需完成备案
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

她也曾应邀参加《吉米秀》(Jimmy Kimmel)和《艾伦秀》(The Ellen Show)。对于一个青春期未到的人来说,有机会上这两个节目还算不错。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

中国民航大学经济管理学院教授李晓津表示,数量迅速增加的航班以及民用航空有限的空域是延误的主要原因。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

The registered urban unemployment rate stood at 4.02 percent at year-end 2016, the lowest level in years.
持续推进大众创业、万众创新。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

提问
['dilidnt]
导演贝尼特·米勒(Bennett Miller)认为卡瑞尔是饰演杜邦的合适人选,但不想让观众一眼就认出他来。他要求造型师比尔·科森(Bill Corso)改变卡瑞尔的外貌。
Developer:Dontnod Entertainment, Square Enix

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
From the themed collection: 浙民投与佳兆业“生化”危机再起
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

也许你在地铁上上见过各种着装怪异迥异的角色出现,可应该没人在月台上见过大熊猫成群结队吧。
Widely misunderstood as a biopic about the novelist David Foster Wallace, Mr. Ponsoldt’s film is a comedy of journalistic bad manners and a bitter, knowing satire of the machinery of literary fame. Jesse Eisenberg and Jason Segel use the conventions of the buddy movie to perfect a new subgenre: the frenemy film.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

I wonder why LeBron James doesn't wear those weird things on his biceps and shoulder anymore. Well, actually I bet he doesn't wear them because they're useless.
Yao Zhenhua, the chairman of Baoneng Group and the biggest riser since 2015, saw his wealth shoot up 820 percent to $17.2 billion, elevating him to fourth in the overall list.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

Emerging market exports have been declining in dollar terms since October 2014, a far longer, if less extreme, losing streak than during the 2008-09 global financial crisis, as the first chart shows.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: 解读2015年松木家具行业发展趋势
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

n. [宗
Two days ago here in Brazil, we were shocked when we spent some time with some children living on the streets. And this is what one child told us: "I wish I was rich and if I were, I would give all the street children food, clothes, medicine, shelter and love and affection." 在巴西,我被2天前见到的情景震惊了,那时我和当地的小孩在玩耍,其中一个小孩说:“我希望我能富裕起来,然后我会给这个街道所有的小孩饭吃,给他们衣服穿,医疗,住房和爱”。
One more scientific group, in Britain, that curates the world’s temperature record is scheduled to report in the coming weeks.
格温o史蒂芬尼的广告在好几个应用上同时推出,其中就有总部位于硅谷的短信应用Tango。Tango主要通过用户收件箱里的广告赚钱,但它已采用了Swyft的平台,该公司广告和平台副总裁理查德o拉百特表示,这类广告非常契合人们使用Tango的方式。一年前,Tango决定不再卖贴纸了,因为向用户要钱总会带来很多摩擦。拉百特称:“在人们沟通过程中放上一道‘留下买路钱’的大门绝不是我们希望带给用户的体验。”所以,就由Swyft来提供这种广告吧。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

For almost everyone else, it was a year of frustration against a backdrop of better-than-average returns for the most popular index in the land.
注册人数:503人

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

It's time to make New Year resolutions for traveling! Backpacker bible Lonely Planet has published its annual list of best value destinations in 2017 for people looking for wallet-friendly sightseeing experiences. Take a look.
Seychelles
Historical and fictional films each have their own strengths when it comes to storytelling. Every now and then, though, movies pop up that don't quite fit into either category. The stories are wildly unrealistic, but they carry an inkling of truth between their pages. While these are some of the most interesting films out there, viewers often don't even know that what they're watching really happened. Well, wonder no more! Keep reading to learn about some of Hollywood's zanier scripts that took their inspiration from good old-fashioned real-life drama.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

courage(n 勇气)
201207/191926.shtml男子400米、1500米自由泳——孙杨
No.5: What Made Phelps So Happy?

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Between 1991 and 2010, the cancer mortality rate fell by a whopping 20%, which is more than 10% a decade. One day we will say goodbye to cancer for good.
It plans to help at least 130,000 rural people cast off poverty and relocate 163,000 residents in 2017.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
From the themed collection: 北京市经济一季度“开门红”
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

“It suggests that people put more weight on what happened to themselves and less weight on other information that might be available,”Koudijs says. The more personally removed people are from an important event, the less it is to affect their appetite for risk.
在其他地方,澳大利亚最近推出了提高基金定价透明度的改革措施,这推动了ETF的快速增长。
n. 港口,避难所,安息所 v. 安置 ... 于港中,

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

The details of her character are being kept under wraps.
In dollar terms, imports plunged 18.8 per cent last month to $114.19, from a 7.6 per cent drop in January and versus an expected drop of 3.6 per cent.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

The book reflects growing anxiety in some quarters about the possible negative impact of automation on jobs, from manufacturing to professional services. The subtitle of its UK edition warns of “the threat of mass unemployment” and, in the US edition, foresees “a jobless future”.
2016年观影人数达到13.7亿人次,同比增长近8.9%。
But the duo topped the trending celebrities section followed by 'X Factor' judges Gary Barlow and Tulisa.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Wang studied computer programming while growing up in China. After college, she hoped to move to the U.S. to start her career. The next year, the Chinese Students Protection Act was passed and Wang got her master's in computer science at University of Houston. She worked at several Silicon Valley startups (and launched her own, iBizWomen.com) until September 11, 2001. The attack inspired her to create Binary Group, a technology consulting company that works with the Federal Government. Over the past 16 years, Binary has helped its clients save piles of money -- like the Army 20th Support Command, which cut $60 million over five years for its satellite communication bandwidth requirements.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

2013年排名:12
今年选股遇到困难,部分原因在于市场顶部高度集中。苹果、伯克希尔o哈撒韦、强生、微软和英特尔这五只股票占去了市场涨幅的20%。如果你未持有上述股票,几乎就没有机会分享这场增长盛宴,而正是这几家公司的增长推高了标普500指数。市场上大部分股票的表现要逊色得多。研究公司路佛集团称,标普1500综合指数成分股中,仅有30%的个股跑赢了该指数。上次出现这样的景象,那还是1999年的事。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

学员平均年龄:36岁(英语授课项目)
这一消息来自英国时装协会,协会在时装周前对设计师进行了调查,发现在9月份的时装周登场的80名设计师中没有一位会使用皮草。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
From the themed collection: 北京首批限价房项目面世
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

女性地位继续上升。
全国工商联汽车经销商会数据显示,自2014年进口现代中国经销商网络已经缩减了一半。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
From the themed collection: 标准变严格倒逼家具行业洗牌
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

游戏平台:Xbox One、Xbox 360、PS4、PS3 、PC
Yao Zhenhua, the chairman of Baoneng Group and the biggest riser since 2015, saw his wealth shoot up 820 percent to $17.2 billion, elevating him to fourth in the overall list.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

6.派对应有尽有——只要你有时间

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

亚太地区是地区国家共有的家园,我们不希望、也不愿意看到冷战思维下所谓“选边站队”的事情发生。
如果说2017年是政策制定者们开始担心“无保障无产阶级”(precariat)人数增长的一年,那么2018年将是他们尝试为此做些什么的一年。
China's economy grew last month, according to a closely-monitored PMI series - which indicated growth for the first time in four months.
你可以在AskMen.com网站上看到完整榜单。以下是最性感女人前十名:

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

我曾见过的超级优秀的老板们,都对他们的工作极具热情,他们同工作共生活共呼吸,尽最大努力将工作做到最好。与此同时,他们还有工作之外的生活。他们懂得家庭和工作或者玩和工作之间的平衡度。他们为员工们如何做到生活和工作之间平衡做了一个很好的表率。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

宾夕法尼亚州立大学的气候科学家迈克尔·E·曼恩(Michael E. Mann)在电子邮件中说,“如果不是由于燃烧化石燃料所产生的、导致地球变暖的气体排放越来越多的原因,在上千年史无前例的几十年较暖期间、创纪录地变暖的十年中,看到变暖的又一个记录年度,是非常不可能的。”
impresar,意大利语,意为管理+o表名词,“人,物或状态”→(娱乐圈的)经理人
其他的欧洲国家生活成本在增长,排名有进步。伦敦上升了5个名次,并且进入前十。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

时间:2010-01-26 编辑:vicki
在这份榜单的前二十人中,C罗和梅西是仅有的两名足球运动员,此外,这份榜单上也没有任何女性运动员入围。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

General Motors is helping fuel the improved jobs outlook in the Grand Canyon State. In March, the automaker announced plans to build the company’s fourth Information Technology Innovation Center in Phoenix suburb Chandler. GM is expected to hire 1, 000 workers, mainly consisting of software developers, database administrators and systems analysts for the new center. “The greater Phoenix area is a fantastic hub of emerging technical talent – from university graduates to working professionals, ” said GM CIO Randy Mott in a release announcing the move.
camp(n 田野,营地),aign名词后缀-营地-备战的地方

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 一二线城市购房标准不断升级
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

If we ask "What salary are you looking for?" say you're flexible, or say it depends on the responsibilities of the job. Try not to name a salary unless we really push you, because that gives us a leg up in the negotiating.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

['pre]
约翰奥瑟兹(John Authers)
单词affection 联想记忆:

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

[st?:]
德马库斯-考辛斯、塞尔吉-伊巴卡和路易斯-威廉姆斯的交易早在截止时间——美国东部时间周四下午3点之前就已经完成了,在余下完成压哨交易的角色球员里,只有像泰-吉布森和PJ-塔克算是相对大牌的球员了。
5. Sunset
办事处副局长卢华东说:“自治区已投资40亿元人民币(约合6亿美元),用于推动贫困地区特色的产业,去年重新安置了77000名贫困人口。”

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

One difficulty in assessing the potential for ETFs in Asia, say experts at the largest asset management houses, is both the disproportionate size of the Japanese market within the region and the role played by the Bank of Japan, which distorts the market as it buys ¥6tn ($54bn) of ETFs a year.
There are 15 Chinese brands in the top 100, one more than last year and a sharp rise on a decade ago, when China Mobile was the only Chinese brand.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

5.谷歌网站管理员工具
Mavericks owner Mark Cuban has made riskier bets than this, though, and he didn't part with much of consequence (Justin Anderson and a fake first-round pick) for a shot at working Noel into a lob-finishing/rim-protecting life as the next Tyson Chandler.
要让产品显得很“酷”并不是唯一的目的。科技行业如果想让我们身体的更多部位连上网络,那么安全问题和隐私问题,尤其是顾客数据管理问题,依旧需要慎重考虑。正如《经济学人》(The Economist)所说,蓬勃发展的传感器的魅力,以及可穿戴设备的算法,分散了人们对于其他要素的关注。这些关键的其它要素包括:“标准、互通性、一体化、数据管理”,以及“知识产权、执行标准”。对国家安全局(National Security Administration)而言,这些技术发展都必须以网络安全为前提。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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No details have been given about the content of the leaflets, though propaganda sent in the past has denounced North Korea's ruling family.
Instead it ticked upward slightly to 8.3 per cent.

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